Meta-Analysis Persistent Human Papillomavirus Infection and Cervical Neoplasia: A Systematic Review and Meta-Analysis

نویسندگان

  • Jill Koshiol
  • Lisa Lindsay
  • Jeanne M. Pimenta
  • Charles Poole
  • David Jenkins
  • Jennifer S. Smith
چکیده

Detection of persistent cervical carcinogenic human papillomavirus (HPV) DNA is used as a marker for cervical cancer risk in clinical trials. The authors performed a systematic review and meta-analysis of the association between persistent HPV DNA and high-grade cervical intraepithelial neoplasia (CIN2-3), high-grade squamous intraepithelial lesions (HSIL), and invasive cervical cancer (together designated CIN2-3/HSILþ) to evaluate the robustness of HPV persistence for clinical use. MEDLINE and Current

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تاریخ انتشار 2007